on Monday, November 30, 2015
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How to Lose Weight Fast: Simple Steps by Steps, Based on Science How to Lose Weight Fast The best methods of losing weight which have the scientific recognition can lose weight quickly and keep it off. Weight loss can be said to be a long term project that needs the constant effort to achieve the best weight-loss effect. The following will tell you a few weight-l… How to Lose Weight Fast The best methods of losing weight which have the scientific recognition can lose weight quickly and keep it off. Weight loss can be said to be a long term project that needs the constant effort to achieve the best weight-loss effect. The following will tell you a few weight-loss methods, which can help you achieve the purpose of weight loss effectively, and meanwhile they are also the best weight-loss methods through scientific research. One bite of meat less for 2 months could help lose 10 pounds Experts point out that each gram of fat contains 9,000 calories. Compared with fat, carbohydrates and protein contain much less calories, which is about 4,000 per gram.Therefore it s unnecessary to eat less for a slim figure. You can eat fresh vegetables, fruits and grains in place of the daily food containing fat (such as cream and eggs). Let’s Get Personal: How Coconut Oil Has Been Helping Me Read More at： How To Use Coconut Oil To Lose Weight? 5 Ways Coconut OiCoconut Oil To Lose Weight Coconut Oil And Weight Loss,Coconut Oil For Weight Loss,Coconut Oil To Lose Weight,Coconut Oil Weight Loss,How To Use Coconut Oil To Lose Weight,How To Use Coconut Oil For Weight Loss
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Al Fosmoe said he “totally blew the presentation” during the Gainesville Area Innovation Network's ShootOut last month.
The slides behind him were too big to read and every time he stepped to the side to read from the computer, the microphone fed back and squealed.
So after the third-place and then second-place winners were announced, he said he wasn't even listening as he talked to a person next to him at dinner when his company was announced as the Top Gun winner — twice.
“Someone at the table said, 'Hey Al, I think that's you.'”
Fosmoe's company, AuxThera, won for its Trimauxil weight-loss product and eating program for dogs.
Despite his presentation, he said the judges recognized both the need that Trimauxil fills and the caliber of the team he put together for his company.
“One of the hardest things in a startup is to fill a need,” he said. “It's easy to create products, but to solve a need is the real challenge. And if you pick a big need and you've got a good solution, then you've got a really good story.”
The need is that 53 percent of dogs are overweight, putting them at risk of diabetes, respiratory problems and heart problems.
Trimauxil is sprinkled over dog food. It works by reducing the size and number of white fat cells and will be used in conjunction with AuxThera's food and snack monitoring program. The product will only be available through licensed veterinarians trained on its use.
Fosmoe started AuxThera in September and is now preparing a “soft launch” of Trimauxil among veterinarians in Florida before a national launch early next year, for which the company is in talks to raise $600,000 from investors.
AuxThera has eight employees and works out of two offices and a lab in the University of Florida Innovation Hub.
Fosmoe has managed drug and medical device manufacturing operations for various biotech companies in Alachua's Progress Park for nearly 30 years.
He got his start as a grad student working in the lab of Bioglass inventor Larry Hench, which would lead to work in companies built around Hench's inventions, including Geltech and USBiomaterials, later working for Ixion and OxThera. He was working as a consultant in recent years, helping companies with process and product improvements, when he was asked to take a look at the technology behind Trimauxil.
“I've been chasing the biotech ring for years and got a lot of stock options that make good wallpaper. It's a high-risk, high-reward business. I've always put a lot of effort into helping these companies move forward and I always wondered what I could do on my own if I put that kind of effort to start up a company and then more importantly develop a team,” he said.
The technology was originally discovered by a local biotech company when used as a control against a compound used to keep genetically modified bacteria alive. The inventor noticed that it reduced the weight of mice in lab tests.
“It was a serendipitous discovery,” he said.
Fosmoe licensed the technology from that company and started AuxThera.
Trimauxil will initially be available for dogs and AuxThera plans to offer a version of its program for cats, which have a higher rate of weight problems.
“I've been very fortunate to work all my life in areas that had meaning and impact on other people's lives,” Fosmoe said.
“This is an area that can make a tremendous impact to people's lives, as important as their pets are. Studies correlate well being of the owners to the vitality and health of their pets as well, so it's a win-win situation.”
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The slides behind him were too big to read and every time he stepped to the side to read from the computer, the microphone fed back and squealed.
So after the third-place and then second-place winners were announced, he said he wasn't even listening as he talked to a person next to him at dinner when his company was announced as the Top Gun winner — twice.
“Someone at the table said, 'Hey Al, I think that's you.'”
Fosmoe's company, AuxThera, won for its Trimauxil weight-loss product and eating program for dogs.
Despite his presentation, he said the judges recognized both the need that Trimauxil fills and the caliber of the team he put together for his company.
“One of the hardest things in a startup is to fill a need,” he said. “It's easy to create products, but to solve a need is the real challenge. And if you pick a big need and you've got a good solution, then you've got a really good story.”
The need is that 53 percent of dogs are overweight, putting them at risk of diabetes, respiratory problems and heart problems.
Trimauxil is sprinkled over dog food. It works by reducing the size and number of white fat cells and will be used in conjunction with AuxThera's food and snack monitoring program. The product will only be available through licensed veterinarians trained on its use.
Fosmoe started AuxThera in September and is now preparing a “soft launch” of Trimauxil among veterinarians in Florida before a national launch early next year, for which the company is in talks to raise $600,000 from investors.
AuxThera has eight employees and works out of two offices and a lab in the University of Florida Innovation Hub.
Fosmoe has managed drug and medical device manufacturing operations for various biotech companies in Alachua's Progress Park for nearly 30 years.
He got his start as a grad student working in the lab of Bioglass inventor Larry Hench, which would lead to work in companies built around Hench's inventions, including Geltech and USBiomaterials, later working for Ixion and OxThera. He was working as a consultant in recent years, helping companies with process and product improvements, when he was asked to take a look at the technology behind Trimauxil.
“I've been chasing the biotech ring for years and got a lot of stock options that make good wallpaper. It's a high-risk, high-reward business. I've always put a lot of effort into helping these companies move forward and I always wondered what I could do on my own if I put that kind of effort to start up a company and then more importantly develop a team,” he said.
The technology was originally discovered by a local biotech company when used as a control against a compound used to keep genetically modified bacteria alive. The inventor noticed that it reduced the weight of mice in lab tests.
“It was a serendipitous discovery,” he said.
Fosmoe licensed the technology from that company and started AuxThera.
Trimauxil will initially be available for dogs and AuxThera plans to offer a version of its program for cats, which have a higher rate of weight problems.
“I've been very fortunate to work all my life in areas that had meaning and impact on other people's lives,” Fosmoe said.
“This is an area that can make a tremendous impact to people's lives, as important as their pets are. Studies correlate well being of the owners to the vitality and health of their pets as well, so it's a win-win situation.”
This entry passed through the Full-Text RSS service - if this is your content and you're reading it on someone else's site, please read the FAQ at http://ift.tt/jcXqJW. from weight loss - Google Newsbr> via Read More:Weight Loss Percentage Calculator
Obese people who lose a substantial amount of weight can significantly slow the degeneration of their knee cartilage, according to a new MRI study presented today at the annual meeting of the Radiological Society of North America (RSNA).
Obesity is a major risk factor for osteoarthritis, a degenerative joint disease that affects more than a third of adults over the age of 60, according to the Centers for Disease Control and Prevention. The knee joint is a common site of osteoarthritis, and in many people the condition progresses until total knee replacement becomes necessary. Aging baby boomers and a rise in obesity have contributed to an increased prevalence of knee osteoarthritis.
"Degenerative joint disease is a major cause of pain and disability in our population, and obesity is a significant risk factor," said the study's lead author, Alexandra Gersing, M.D., from the Department of Radiology and Biomedical Imaging at the University of California, San Francisco. "Once cartilage is lost in osteoarthritis, the disease cannot be reversed."
Dr. Gersing and colleagues recently investigated the association between different degrees of weight loss and the progression of knee cartilage degeneration in 506 overweight and obese patients from the Osteoarthritis Initiative, a nationwide research study focused on the prevention and treatment of knee osteoarthritis. The patients either had mild to moderate osteoarthritis or risk factors for the disease. They were divided into three groups: a control group who did not lose weight, a second group who lost a little weight, and a third group who lost more than 10 percent of their body weight. The researchers then used MRI to quantify knee osteoarthritis.
"Through T2 relaxation time measurements from MRI, we can see changes in cartilage quality at a very early stage, even before it breaks down," Dr. Gersing said.
When the researchers analyzed differences in the quality of cartilage among the three groups over a four-year time span, they found evidence that weight loss has a protective effect against cartilage degeneration and that a larger amount of weight loss is more beneficial.
"Cartilage degenerated a lot slower in the group that lost more than 10 percent of their body weight, especially in the weight-bearing regions of the knee," Dr. Gersing said. "However, those with 5 to 10 percent weight loss had almost no difference in cartilage degeneration compared to those who didn't lose weight."
Substantial weight loss not only slows knee joint degeneration--it also reduces the risk of developing osteoarthritis, Dr. Gersing said. Along with moderate exercise, weight loss is one of the primary interventions against the disease.
"It's most helpful if these lifestyle interventions take place as early as possible," Dr. Gersing said.
In the future, the researchers are planning to study the role of diabetes, which is closely linked with obesity, in cartilage degeneration. They also plan to do an eight-year follow-up with the patient group and look at what effects weight gain may have on the knee joint.
Radiological Society of North America
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on Sunday, November 29, 2015
CHICAGO - Obese people who lose a substantial amount of weight can significantly slow the degeneration of their knee cartilage, according to a new MRI study presented today at the annual meeting of the Radiological Society of North America (RSNA).
Obesity is a major risk factor for osteoarthritis, a degenerative joint disease that affects more than a third of adults over the age of 60, according to the Centers for Disease Control and Prevention. The knee joint is a common site of osteoarthritis, and in many people the condition progresses until total knee replacement becomes necessary. Aging baby boomers and a rise in obesity have contributed to an increased prevalence of knee osteoarthritis.
"Degenerative joint disease is a major cause of pain and disability in our population, and obesity is a significant risk factor," said the study's lead author, Alexandra Gersing, M.D., from the Department of Radiology and Biomedical Imaging at the University of California, San Francisco. "Once cartilage is lost in osteoarthritis, the disease cannot be reversed."
Dr. Gersing and colleagues recently investigated the association between different degrees of weight loss and the progression of knee cartilage degeneration in 506 overweight and obese patients from the Osteoarthritis Initiative, a nationwide research study focused on the prevention and treatment of knee osteoarthritis. The patients either had mild to moderate osteoarthritis or risk factors for the disease. They were divided into three groups: a control group who did not lose weight, a second group who lost a little weight, and a third group who lost more than 10 percent of their body weight. The researchers then used MRI to quantify knee osteoarthritis.
"Through T2 relaxation time measurements from MRI, we can see changes in cartilage quality at a very early stage, even before it breaks down," Dr. Gersing said.
When the researchers analyzed differences in the quality of cartilage among the three groups over a four-year time span, they found evidence that weight loss has a protective effect against cartilage degeneration and that a larger amount of weight loss is more beneficial.
"Cartilage degenerated a lot slower in the group that lost more than 10 percent of their body weight, especially in the weight-bearing regions of the knee," Dr. Gersing said. "However, those with 5 to 10 percent weight loss had almost no difference in cartilage degeneration compared to those who didn't lose weight."
Substantial weight loss not only slows knee joint degeneration--it also reduces the risk of developing osteoarthritis, Dr. Gersing said. Along with moderate exercise, weight loss is one of the primary interventions against the disease.
"It's most helpful if these lifestyle interventions take place as early as possible," Dr. Gersing said.
In the future, the researchers are planning to study the role of diabetes, which is closely linked with obesity, in cartilage degeneration. They also plan to do an eight-year follow-up with the patient group and look at what effects weight gain may have on the knee joint.
###
Co-authors on the study are Martin Solka, Gabby B. Joseph, Ph.D., Benedikt J. Schwaiger, M.D., Ursula R. Heilmeier, M.D., Georg Feuerriegel, John Mbapte Wamba, M.D., Charles E. McCulloch, Ph.D., Michael C. Nevitt, Ph.D., and Thomas M. Link, M.D., Ph.D.
Note: Copies of RSNA 2015 news releases and electronic images will be available online at RSNA.org/press15 beginning Monday, Nov. 30.
RSNA is an association of more than 54,000 radiologists, radiation oncologists, medical physicists and related scientists, promoting excellence in patient care and health care delivery through education, research and technologic innovation. The Society is based in Oak Brook, Ill. (RSNA.org)
For patient-friendly information on musculoskeletal MRI, visit RadiologyInfo.org.
Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.
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on Saturday, November 21, 2015
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